Of concern to any user of Winstrol during a cycle should be its intoxicating effect on the liver . The drug is a 17aa structured steroid , meaning it has been structured in a way which allows it to be orally bio-available, yet this has the negative effect of making Winstrol potentially harmful to the liver. It is therefore paramount the duration of a Winstrol cycle is limited, the dose of the drug is not excessive, the user does not stack it with other hepatotoxic compounds, does not drink alcohol whilst on cycle, and does not use Winstrol if they have an underlying medical condition which effects the livers health. There are supplements available which also help protect the liver (Milk Thistle, Liv-52 etc), and these would be advisable during any Winstrol cycle .
Effective oral dose for the purpose of building muscle mass is a 15-40mg in period of not more than 6-8 weeks. This quantity is sufficient to see the effects. It is mostly used in definition period and pre-competition has a synergistic effect when taken together with testosterone. It has the ability to bind to SHBG (a substance that reduces the effectiveness of extracorporeal testosterone), releasing a greater amount of testosterone in the blood. Turinabol has a half-life of 16 hours, which is quite a long time for oral anabolic steroid. Therefore, it is necessary to divide the daily dose. Recent experience pointed to the relatively short period of steroid detection in urine - only 25-30 days. However, latest backstage information showed that athletes who have taken this favourite substance were positive after 33 days after its discontinuation, for which they received a disqualification for up to two years.
Drugs such as Nolvedex bind to the oestrogen receptors , therefore reducing the effects of the heightened oestrogen in the body. Such drugs do nothing to reduce the amount of oestrogen in the body; they merely reduce its effects via competition for the receptors . If the user wishes to reduce the amount of oestrogen they should look to drugs such as proviron and anastrozole , which are known as anti-aromatases - . they lower the conversion of the steroid to oestrogen and therefore reduces the overall amount of oestrogen present.