Medications for people, including aspirin, don't necessarily act the same in pets as they do in people. Humans often take enteric-coated aspirin, but it is unwise to use these tablets in pets. Enteric coating prevents aspirin from dissolving easily so that it can sit in the pet's stomach for a long time. It's possible for aspirin to "collect" in the stomach, exposing the pet to a toxic dose. It's better to use aspirin, like Excel Aspirin , specifically developed for dogs, or to use a powdery, uncoated aspirin that dissolves easily. It's never wise to use aspirin without specific veterinary instruction.
Treatment: If a pancreatic or liver tumor is identified and able to be surgically excised, the skin lesions may normalize for an extended period of time, but because these tumors metastasize (spread to other areas of the body) quickly, surgery is not curative. In cases of end stage liver disease, surgery is not possible, and the goal of therapy is to increase quality of life and decrease uncomfortable skin lesions with supportive care and addressing the nutritional abnormalities. Supportive care includes supplementing protein and necessary minerals and enzymes through the diet and oral supplements or by weekly intravenous amino acid infusions that are performed in the hospital on an outpatient basis until improvement in the skin is noted. Unfortunately, despite the supportive care, the disease will progress.