Role of ecdysteroids

Facility Advisory Group
The mission of the Facility Advisory Group is to provide guidance and feedback to the facility regarding the most effective use of its resources to meet research demands.

James R. Alfano, PhD
Phone: (402) 472-0395
Email: jalfano2@
Alfano Lab website

Oleh Khalimonchuk, PhD
Phone: (402) 472-8060
Email: okhalimonchuk2@
Khalimonchuk Lab website

Yongfeng Lu, .
Phone: 402-472-8323
Email: ylu2@
Visit Faculty Webpage

Matthew Wiebe, .
Phone: (402) 472-4154
Email: mwiebe2@
Visit Faculty Webpage

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Melanin (skin pigmentation) has also been reported to have its production reduced secondary to reduces production of the enzyme tyrosinase , which catalyzes the rate-limiting step in melanin synthesis. [44] This study noted that in B16F1 melanoma cells that incubation with up to 200ug/mL failed to exert cytotoxic effects and reduced melanin content at 25ug/mL (to 67% of control) and more-so at 50ug/mL and 100ug/mL reducing melanin down to 40% of control cells (with no significant difference between these two concentrations). [44] mRNA of tyrosinase was potently reduced to +/-% of control with 25ug/mL with higher doses being insignificantly better. [44]

Role of ecdysteroids

role of ecdysteroids

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