Inhaled corticosteroid mode of action

Patients requiring oral corticosteroids should be weaned slowly from systemic corticosteroid use after transferring to ALVESCO. Prednisone reduction can be accomplished by reducing the daily prednisone dose by mg on a weekly basis during ALVESCO therapy [see DOSAGE AND ADMINISTRATION ]. Lung function (FEV 1 or AM PEFR), beta-agonist use, and asthma symptoms should be carefully monitored during withdrawal of oral corticosteroids. In addition to monitoring asthma signs and symptoms, patients should be observed for signs and symptoms of adrenal insufficiency, such as fatigue, lassitude , weakness, nausea and vomiting, and hypotension .

Advair (Fluticasone + Salmeterol) :    The original combination inhaler is still the most popular.     Basically it combines a steroid with a long acting beta adrenergic (LABA).   The steroid  controls inflammation while the LABA keeps your lungs relaxed around the clock.   The combination of these medicines has worked wonders for many asthmatics.  The best part of this medicine is all you need to do is take one puff in the morning and one before bed.   This greatly improves complaince, and that alone I think has benefited many asthmatics.

Use of QVAR with a spacer device in children less than 5 years of age is not recommended. In vitro dose characterization studies were performed with QVAR 40 mcg/actuation with the OptiChamber and AeroChamber Plus ® spacer utilizing inspiratory flows representative of children under 5 years old. These studies indicated that the amount of medication delivered through the spacing device decreased rapidly with increasing wait times of 5 to 10 seconds as shown in Table 2. If QVAR is used with a spacer device, it is important to inhale immediately.

Inhaled corticosteroid mode of action

inhaled corticosteroid mode of action

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